Ke-Fei Shen Selected Research

kelatorphan

9/2008	Low doses of cyclic AMP-phosphodiesterase inhibitors rapidly evoke opioid receptor-mediated thermal hyperalgesia in naïve mice which is converted to prominent analgesia by cotreatment with ultra-low-dose naltrexone.
9/2007	Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice.

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Ke-Fei Shen Research Topics

Disease

2	Hyperalgesia 09/2008 - 09/2007
1	Opioid-Related Disorders (Opiate Addiction) 09/2007

Drug/Important Bio-Agent (IBA)

2	Opioid Peptides (Opioid Peptide)IBA 09/2008 - 09/2007
2	Opioid Receptors (Opioid Receptor)IBA 09/2008 - 09/2007
2	Naltrexone (ReVia)FDA LinkGeneric 09/2008 - 09/2007
2	Opioid Analgesics (Opioids)IBA 09/2008 - 09/2007
2	kelatorphanIBA 09/2008 - 09/2007
1	RolipramIBA 09/2008
1	Cyclic AMP (AMP, Cyclic)IBA 09/2008
1	Caffeine (No Doz)FDA LinkGeneric 09/2008
1	EnzymesIBA 09/2008
1	Phosphodiesterase InhibitorsIBA 09/2008
1	1-Methyl-3-isobutylxanthine (1 Methyl 3 isobutylxanthine)IBA 09/2008
1	Indicators and Reagents (Reagents)IBA 09/2007
1	Narcotic Antagonists (Opioid Antagonists)IBA 09/2007
1	G(M1) GangliosideIBA 09/2007
1	GlycolipidsIBA 09/2007
1	norbinaltorphimineIBA 09/2007
1	mu Opioid Receptors (mu Opioid Receptor)IBA 09/2007
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 09/2007
1	AutoreceptorsIBA 09/2007
1	Morphine (MS Contin)FDA LinkGeneric 09/2007
1	Naloxone (Narcan)FDA LinkGeneric 09/2007

Therapy/Procedure

2	Analgesia 09/2008 - 09/2007